| Name | What | Region | Country | Lat | Long | Elev ft. | Pop est |
|---|---|---|---|---|---|---|---|
| Solo | city | Missouri | United States | 37.23 | -91.95 | 1161 | |
| Sonora | city | Missouri | United States | 40.50 | -95.66 | 898 | |
| Sorrell | city | Missouri | United States | 40.22 | -93.02 | 938 | |
| Souder | city | Missouri | United States | 36.79 | -92.46 | 853 | |
| Soulard | city | Missouri | United States | 38.61 | -90.21 | 830 | |
| South Blanchard (historical) | city | Missouri | United States | 40.58 | -95.22 | 1036 | |
| South Carrollton | city | Missouri | United States | 39.34 | -93.50 | 830 | |
| South Drexel | city | Missouri | United States | 38.48 | -94.61 | 1007 | |
| South Fork | city | Missouri | United States | 36.63 | -91.96 | 1053 | |
| South Greenfield | city | Missouri | United States | 37.38 | -93.84 | 918 | |
| South Lee | city | Missouri | United States | 38.89 | -94.38 | 997 | |
| South Liberty | city | Missouri | United States | 39.20 | -94.39 | 830 | |
| South Lineville | city | Missouri | United States | 40.58 | -93.52 | 1079 | |
| South Point (historical) | city | Missouri | United States | 38.54 | -90.98 | 830 | |
| South River | city | Missouri | United States | 39.83 | -91.45 | 830 | |
| South Shore | city | Missouri | United States | 38.87 | -90.52 | 830 | |
| South Troy | city | Missouri | United States | 38.96 | -90.99 | 830 | |
| South Van Buren | city | Missouri | United States | 36.99 | -91.01 | 830 | |
| South West City | city | Missouri | United States | 36.51 | -94.61 | 967 | |
| Southard | city | Missouri | United States | 37.54 | -92.34 | 1099 | |
| Southhampton | city | Missouri | United States | 38.59 | -90.30 | 830 |