| Name | What | Region | Country | Lat | Long | Elev ft. | Pop est |
|---|---|---|---|---|---|---|---|
| Seaton | city | Missouri | United States | 37.81 | -91.60 | 1099 | |
| Sebree | city | Missouri | United States | 39.13 | -92.53 | 830 | |
| Seckman | city | Missouri | United States | 38.40 | -90.43 | 830 | |
| Sedalia | city | Missouri | United States | 38.70 | -93.23 | 912 | |
| Sedan (historical) | city | Missouri | United States | 36.86 | -92.31 | 931 | |
| Sedgewickville | city | Missouri | United States | 37.52 | -89.91 | 830 | |
| Sedgwick | city | Missouri | United States | 40.01 | -92.91 | 984 | |
| Seebarger | city | Missouri | United States | 38.86 | -90.54 | 830 | |
| Seeburger | city | Missouri | United States | 38.87 | -90.51 | 830 | |
| Seligman | city | Missouri | United States | 36.52 | -93.94 | 1669 | |
| Selkirk | city | Missouri | United States | 36.72 | -89.45 | 295 | |
| Sellers | city | Missouri | United States | 40.07 | -91.67 | 830 | |
| Selma | city | Missouri | United States | 38.15 | -90.34 | 830 | |
| Selmore | city | Missouri | United States | 36.97 | -93.23 | 1669 | |
| Selsa | city | Missouri | United States | 39.05 | -94.34 | 830 | |
| Senate Grove (historical) | city | Missouri | United States | 38.58 | -91.33 | 830 | |
| Senath | city | Missouri | United States | 36.13 | -90.16 | 249 | |
| Seneca | city | Missouri | United States | 36.84 | -94.61 | 895 | |
| Seneca Quapaw Agency (historical) | city | Missouri | United States | 36.90 | -94.61 | 1026 | |
| Seney | city | Missouri | United States | 39.85 | -92.58 | 898 | |
| Sent Loisos | city | Missouri | United States | 38.63 | -90.20 | 416 | |
| Sent Luisas | city | Missouri | United States | 38.63 | -90.20 | 416 | |
| Sent-Luis | city | Missouri | United States | 38.63 | -90.20 | 416 | |
| Sentinel | city | Missouri | United States | 37.79 | -93.30 | 938 | |
| Sentluisa | city | Missouri | United States | 38.63 | -90.20 | 416 | |
| Sequiota | city | Missouri | United States | 37.15 | -93.24 | 1197 | |
| Sereno | city | Missouri | United States | 37.80 | -89.85 | 830 | |
| Service | city | Missouri | United States | 37.97 | -91.15 | 830 | |
| Settletown | city | Missouri | United States | 37.95 | -90.60 | 830 | |
| Seventysix | city | Missouri | United States | 37.72 | -89.61 | 830 | |
| Sewell Ford | city | Missouri | United States | 38.19 | -91.56 | 830 | |
| Seybert | city | Missouri | United States | 37.52 | -93.77 | 830 | |
| Seymour | city | Missouri | United States | 37.15 | -92.77 | 1669 |